Chronic kidney disease (CKD) nutrition requires specialized formulations that balance protein needs with mineral restrictions.
Nutritional Challenges in CKD
Conflicting Requirements:
- Need adequate protein (prevent malnutrition)
- Limit protein waste products (reduce uremic toxins)
- Restrict phosphorus and potassium
- Maintain adequate calories
Stage-Specific Needs:
- Stages 1-3: Moderate protein restriction
- Stages 4-5 (pre-dialysis): Careful protein management
- Dialysis: Increased protein needs
Renal Formulation Guidelines
Protein Management
Pre-Dialysis (Stage 1-4):
- Protein: 0.6-0.8g per kg body weight
- High biological value proteins preferred
- Minimize protein waste products
Dialysis (Stage 5):
- Protein: 1.0-1.2g per kg body weight
- Higher needs due to dialysis losses
- Emphasis on essential amino acids
Phosphorus Control (Critical)
Target: <800mg phosphorus daily
- Use protein sources with low phosphorus
- Avoid phosphorus-containing additives
- Consider phosphate binders if needed
Phosphorus Content per 20g Protein:
- Whey protein isolate: ~30mg (LOW
- preferred)
- Egg white protein: ~10mg (VERY LOW
- best)
- Soy protein: ~120mg (HIGH
- avoid)
- Casein: ~160mg (HIGH
- avoid for renal)
Potassium Restriction
Target: 2,000-3,000mg daily total intake
- Select low-potassium protein sources
- Monitor electrolyte content carefully
Energy Requirements
High Calorie Density:
- CKD patients often have poor appetite
- 30-35 kcal per kg body weight needed
- Add healthy fats for calorie density without protein increase
Renal-Specific Product Formulation
Ideal Composition (Per Serving):
- Protein: 15-20g (high biological value)
- Phosphorus: <50mg
- Potassium: <150mg
- Sodium: <200mg
- Calories: 300-400 (calorie-dense)
Preferred Protein Sources:
- Egg white protein (low phosphorus, high quality)
- Whey protein isolate (acceptable phosphorus)
- Essential amino acid blends (minimum waste)
Avoid:
- Casein (high phosphorus)
- Soy protein (high phosphorus and potassium)
- Nuts and seeds (high phosphorus and potassium)
Clinical Applications
Pre-Dialysis:
- Moderate protein, controlled minerals
- Slows disease progression
- Prevents malnutrition
Hemodialysis:
- Higher protein (replaces dialysis losses)
- Low phosphorus critical
- Often taken post-dialysis
Peritoneal Dialysis:
- Highest protein needs (protein loss in dialysate)
- More flexible mineral restrictions
Renal Product Manufacturing
UNO Nutrition manufactures medical-grade renal nutrition for:
- Hospital nephrology departments
- Dialysis centers
- Pharmacy medical nutrition sections
- Renal patient support programs
Our formulations meet clinical guidelines and are developed in consultation with renal dietitians and nephrologists.
ISO 22000 and GMP certified manufacturing ensures pharmaceutical-grade quality control for medical nutrition applications.